Understanding vulnerability for depression from a cognitive neuroscience perspective: a reappraisal of attentional factors and a new conceptual framework

We propose a framework to understand increases in vulnerability for depression after recurrent episodes that links attention processes and schema activation to negative mood states, by integrating cognitive and neurobiological findings. Depression is characterized by a mood-congruent attentional bias at later stages of information processing. The basic idea of our framework is that decreased activity in prefrontal areas, mediated by the serotonin metabolism which the HPA axis controls, is associated with an impaired attenuation of subcortical regions, resulting in prolonged activation of the amygdala in response to stressors in the environment. Reduced prefrontal control in interaction with depressogenic schemas leads to impaired ability to exert attentional inhibitory control over negative elaborative processes such as rumination, leading in turn to sustained negative affect. These elaborative processes are triggered by the activation of negative schemas after confrontation with stressors. In our framework, attentional impairments are postulated as a crucial process in explaining the increasing vulnerability after depressive episodes, linking cognitive and biological vulnerability factors. We review the empirical data on the biological factors associated with the attentional impairments and detail how they are associated with rumination and mood regulation. The aim of our framework is to stimulate translational research

The influence of psychological resilience on the relation between automatic stimulus evaluation and attentional breadth for surprised faces

The broaden-and-build theory relates positive emotions to resilience and cognitive broadening. The theory proposes that the broadening effects underly the relation between positive emotions and resilience, suggesting that resilient people can benefit more from positive emotions at the level of cognitive functioning. Research has investigated the influence of positive emotions on attentional broadening, but the stimulus in the target of attention may also influence attentional breadth, depending on affective stimulus evaluation. Surprised faces are particularly interesting as they are valence ambiguous, therefore, we investigated the relation between affective evaluation-using an affective priming task-and attentional breadth for surprised faces, and how this relation is influenced by resilience. Results show that more positive evaluations are related to more attentional broadening at high levels of resilience, while this relation is reversed at low levels. This indicates that resilient individuals can benefit more from attending to positively evaluated stimuli at the level of attentional broadening

The relationship between time perspective and subjective well-being of older adults

Time perspective is crucial for our present and future plans, and for the way we act in the present. The aim of this study was to investigate the relationship between time perspective and subjective well-being in older adults. The sample of our questionnaire study consisted of 149 older adults aged between 65 and 96 years. Time perspective was measured with the Zimbardo Time Perspective Inventory. The five time perspective dimensions were related to four specific aspects of subjective well-being (positive affect, negative affect, life satisfaction and depression). Future-oriented older persons had a more positive affect. Older adults who were positively oriented towards the past appeared to be more satisfied with life. A hedonistic view of the present was related to a high positive affect:Older persons with a Past-Negative perspective were more likely to experience negative affect and depressive feelings, along with a lower level of positive affect and satisfaction with life. The Present-Fatalistic time perspective correlated with more depressive symptoms. The findings emphasize the relevance of time perspective styles for the subjective well-being, which has specific implications for the way caregivers could interact with older adults to enhance quality of life

Effects of positive mood on attentional breadth for emotional stimuli

Although earlier studies have related positive emotions to affentional broadening, recent findings point out the complexity of this relation and show that these broadening effects interact with factors such as characteristics of the information that is presented. Besides stimuli characteristics, individual characteristics such as the presence of depressive symptoms could also influence the broadening effects as depressive symptoms have previously been related to a more narrow attentional scope. Therefore, the aim of this study was to further investigate the affentional broadening effects of positive emotions, testing whether this is influenced by the emotional valence of the information presented and secondly, how the presence of depressive symptoms might interact with this relationship. We used a performance based measure to assess fluctuations in affentional broadening for positive, neutral, and negative stimuli. We assessed the presence and severity of depressive symptoms in an unselected study sample and tested whether these symptoms moderate the relationship between induced positive mood and affentional breadth for emotional information. Results showed no direct relation between positive mood and affentional breadth, regardless of the emotional valence of the stimuli. However, the presence of depressive symptoms moderated this relationship in such a way that among low levels of depressive symptoms, positive mood was related to attentional broadening specifically when positive information was presented, while at high levels of depressive symptoms this relation was reversed. The current findings suggest that both stimuli characteristics, individual characteristics and their interplay should be taken into account when investigating the broadening effects of positve emotions

Internal sensations as a source of fear: exploring a link between hypoxia and flight phobia

Although flight phobia is very common in the general population, knowledge of the underlying mechanisms is limited. The aim of the current study is to determine whether hypoxia is selectively associated with flight anxiety. We wanted to explore levels of oxygen saturation (SpO2) and the associated subjective somatic sensations in flight phobics and controls. The data collected in this study were obtained from 103 participants: 54 had flight phobia, 49 were controls. SpO2 as well as a subjective report of somatic sensations and anxiety were measured during short haul flights, both at ground level and at cruising altitude. Results indicated that both flight phobics and controls showed a comparable clinical significant decrease in SpO2 from sea level to cruising altitude. Next, at ground level the flight phobic group reported more somatic sensations, most likely due to the elevated levels of anxiety at that point. However, at cruising altitude the flight phobic group still reported more somatic sensations while the level of anxiety was no longer significantly different from controls. This finding points to altered symptom perception in flight phobia and stresses the importance of somatic sensations in this particular phobia

Feeling happy when feeling down : the effectiveness of positive mental imagery in dysphoria

Background and objectives Mental imagery can evoke strong emotional responses, but imagery perspective can influence the response, with observer perspective reducing emotionality. This is important provided that positive imagery can be an effective mood repairing strategy in healthy individuals. However, (sub-clinical) depressed individuals tend to spontaneously adopt an observer perspective. We investigated whether positive imagery would result in a similar emotional response in dysphoric and non-dysphoric individuals when instructed and trained to use field perspective imagery. Additionally, we compared the emotional response in dysphoric individuals who received instructions to dysphoric individuals who received no instructions on processing mode during positive memory recall. Methods Dysphoric and non-dysphoric individuals completed a mood induction procedure imagining positive or neutral memories. They received instructions and practice in the use of field perspective imagery. An additional control group of dysphoric individuals recalled positive memories without receiving instructions on processing mode. Results Dysphoric and non-dysphoric individuals who received instructions on field perspective imagery reported similar use of field and observer perspective imagery, and a similar positive emotional response. Dysphoric individuals who did not receive specific instructions, as compared to those who did, reported greater use of observer perspective and lower levels of positive affect afterwards. Limitations A dysphoric sample limits generalization to clinically depressed individuals, although these individuals are at risk for developing depression. However, mental imagery used in relapse prevention is likely targeting sub-clinical populations. Conclusions Providing practice in field perspective imagery could potentially improve the effectiveness of positive memory recall as a mood repair strategy in (sub-clinically) depressed individuals, and may therefore have important therapeutic benefits.</p

Mental imagery of positive and neutral memories : a fMRI study comparing field perspective imagery to observer perspective imagery

Imagery perspective can influence what information is recalled, processing style, and emotionality; however, the understanding of possible mechanisms mediating these observed differences is still limited. We aimed to examine differences between memory recall from a field perspective and observer perspective at the neurobiological level, in order to improve our understanding of what is underlying the observed differences at the behavioral level. We conducted a fMRI study in healthy individuals, comparing imagery perspectives during recall of neutral and positive autobiographical memories. Behavioral results revealed field perspective imagery of positive memories, as compared to observer perspective, to be associated with more positive feelings afterwards. At the neurobiological level, contrasting observer perspective to field perspective imagery was associated with greater activity, or less decrease relative to the control visual search task, in the right precuneus and in the right temporoparietal junction (TPJ). Greater activity in the right TPJ during an observer perspective as compared to field perspective could reflect performing a greater shift of perspective and mental state during observer perspective imagery than field perspective imagery. Differential activity in the precuneus may reflect that during observer perspective imagery individuals are more likely to engage in (self-) evaluative processing and visuospatial processing. Our findings contribute to a growing understanding of how imagery perspective can influence the type of information that is recalled and the intensity of the emotional response. Observer perspective imagery may not automatically reduce emotional intensity but this could depend on how the imagined situation is evaluated in relation to the self-concept. (C) 2016 Elsevier Inc. All rights reserved

The positivity effect in older adults : the role of affective interference and inhibition

Objectives: Research shows that aging often involves a decrease in the experience of negative affect and might even be associated with a stabilization or an increase in experience concerning positive affect. As it has been suggested that these changes could be related to the processing of emotional information, the aim of this study was to investigate interference and inhibition toward sad and happy faces in healthy elderly people compared to a younger population. Method: We used an affective modification of the negative priming task. If interference is related to enhanced inhibition, reduced interference from negative stimuli and a related weakened inhibition toward negative stimuli in the elderly group would be in line with the positivity hypothesis. Results: As expected, the results indicated that interference from negative stimuli was significantly lower in older adults as compared to younger adults, whereas this was not the case for positive stimuli. Moreover, at inhibitory level a significantly reduced processing of negative stimuli was observed only in the older adult group, whereas there was no such effect in the case of positive material. Conclusion: These observations are indicative for a decreased negative bias in older adults at information processing level. This provides new insights with regard to age-related differences in emotion processing